Terameprocol, also known as EM-1421, is a semi-synthetic tetra-methylated derivative of nordihydroguaiaretic acid (NDGA) and transcriptional inhibitor with potential antiviral, antiangiogenic, and antineoplastic activities. Terameprocol competes with the transcription factor Sp1 for specific Sp1 DNA binding domains within gene promoter regions during DNA synthesis. In virally-infected cells, blocking of the Sp1 binding site suppresses Sp1-regulated viral promoter activity and gene expression, thereby inhibiting viral transcription and replication.
1、产品物理参数：
|
常用名 |
英文名 |
||
|
CAS号 |
分子量 |
358.471 |
|
|
密度 |
1.0±0.1 g/cm3 |
沸点 |
458.5±40.0 °C at 760 mmHg |
|
分子式 |
C22H30O4 |
熔点 |
无资料 |
|
闪点 |
108.8±34.2 °C |
|
|
密度
1.0±0.1 g/cm3
沸点
458.5±40.0 °C at 760 mmHg
分子式
C22H30O4
分子量
358.471
闪点
108.8±34.2 °C
精确质量
358.214417
PSA
36.92000
LogP
5.86
蒸汽压
0.0±1.1 mmHg at 25°C
折射率
1.522
terameprocol
tetramethyl Nordihydroguaiaretic Acid Exclusive
4-[(2R,3S)-4-(3,4-Dimethoxyphenyl)-2,3-dimethylbutyl]-1,2-dimethoxybenzene
tetramethyl Nordihydroguaiaretic Acid
Benzene, 4-[(2R,3S)-4-(3,4-dimethoxyphenyl)-2,3-dimethylbutyl]-1,2-dimethoxy-
