简介：W146 TFA是鞘氨醇-1-磷酸受体1(S1PR1)的选择性拮抗剂,EC50值为398 nM。
W146 TFA物理化学性质：
分子式 C18H28F3N2O6P
分子量 456.4
储存条件 -20°C，密闭，干燥
W146 TFA详细介绍：
产品名称： [Perfemiker]W146 trifluoroacetate salt,98%
英文名称： W146 trifluoroacetate salt
品牌： Perfemiker
CAS号： 909725-62-8
纯度： 98%
详细描述： 创赛优选商城提供的W146 trifluoroacetate salt,98%为创赛科技出品的抑制剂,产品稳定,定制速度快,极大地方便了广大科研客户的使用需求。产品包装为1mg。查询关键词:抑制剂，909725-62-8，W146 trifluoroacetate salt,98%，W146 trifluoroacetate salt，博飞美科，Perfemiker，上海，厂家直销。
W146 TFA参考文献：
[1]. M Germana Sanna, et al. Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo. Nat Chem Biol. 2006 Aug;2(8):434-41. Epub 2006 Jul 9.
[2]. Jingjing Liu, et al. 3-amino-4-(3-hexylphenylamino)-4-oxobutyl phosphonic acid (W146), a Selective Antagonist of Sphingosine-1-phospahte Receptor Subtype 1, Enhances AMD3100-stimulated Mobilization of Hematopoietic Stem Progenitor Cells in Animals. J Biochem Pharmacol Res. 2013 Dec; 1(4): 197–203.
[3]. Hang Wang, et al. Sphingosine-1-phosphate promotes the proliferation and attenuates apoptosis of Endothelial progenitor cells via S1PR1/S1PR3/PI3K/Akt pathway. Cell Biol Int. 2018 May 23.
