| 中文名称 |
[优选]Paricalcitol
|
|---|---|
| 中文别名 |
帕立骨化醇;帕立骨化醇 USP标准品;帕立骨化醇-D6;帕立骨化醇标准品;帕立骨化醇（冷藏运输）;帕里醇;1,25-双羟基维他命D2
|
| 英文名称 |
Paricalcitol
|
| 英文别名 |
Paricalcitol;Zemplar;(1R,3R)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5S)-6-Hydroxy-5,6-dimethylhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]cyclohexane-1,3-diol;19-Nor-1alpha,25-dihydroxyvitamin D2;Paracalcin;(1α,3β,7E,22E)-19-Nor-9,10-secoergosta-5,7,22-triene-1,3,25-triol solution;(1α, 3β, 7E,22E)-19-Nor-9,10-secoergosta-5,7,22-triene-1,3,25-triol;Paricalcitol(Zemplar);19-Nor-1,25- dihydroxyvitaMin D2;1α,25-Dihydroxy-19-nor-vitaMin D2;1,25-DihydroxyvitaMin D2 Paricalcitol;Paricalcitol (10 mg) (COLD SHIPMENT REQUIRED)
|
| Cas No. |
131918-61-1
|
| 分子式 |
C27H44O3
|
| 分子量 |
416.64
|
| 包装储存 |
4°C, protect from light, stored under nitrogen *该产品在溶液状态不稳定，建议您现用现配，即刻使用。 |
| 生物活性 |
Paricalcitol, a vitamin D analogue, is a vitamin D receptor agonist, used for the prevention and treatment of secondary hyperparathyroidism (excessive secretion of parathyroid hormone) associated with chronic renal failure. |
|---|---|
| 性状 |
Solid |
| 体外研究(In Vitro) |
Paricalcitol (3×10 M; HP + PC) produces a significant reduction in calcification relative to the observed in cells in HP medium. Paricalcitol causes a reduction in the levels of nuclear β-catenin to a level similar to that observed in control cells. Medlife has not independently confirmed the accuracy of these methods. They are for reference only. |
| 体内研究(In Vivo) |
Paricalcitol (300 ng/kg/day) significantly decreases Tau, and prevents LV dysfunction in mice. Paricalcitol reduces mRNA expression of ANP, fibronectin and collagen III in the TAC-pari mice. Medlife has not independently confirmed the accuracy of these methods. They are for reference only. |
| 运输条件 |
Room temperature or refrigerated transportation. |
| 储存方式 |
4°C, protect from light, stored under nitrogen *该产品在溶液状态不稳定，建议您现用现配，即刻使用。 |
| ClinicalTrial |
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| 参考文献 |
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本文引用：https://www.med-life.cn/product/871873.html
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