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| 产地 | 中国 |
| 品牌 | PrimeGene（普欣） |
| 货号 | 201-13 |
| 用途 | 细胞/科研/抗肿瘤药物 |
| 包装规格 | 5μg |
| 纯度 | > 97 %% |
| CAS编号 | |
| 是否进口 | 否 |
产品名称：Recombinant Human BCA-1/CXCL13（rHuBCA-1/CXCL13）
产品价格：
| 货号 | 规格 | 价格 |
| 201-13 | 5μg | 600 |
| 201-13 | 20μg | 1490 |
| 201-13 | 100μg | 5510 |
| 201-13 | 250μg | 9920 |
| 201-13 | 500μg | 12900 |
| 201-13 | 1mg | 17640 |
技术参数：
| Synonyms | Angie, B lymphocyte chemoattractant, CXC chemokine BLC, Small-inducible cytokine B13 |
| Accession | O43927 |
| GeneID | 10563 |
| Source | Escherichia coli. |
| Molecular Weight | Approximately 10.3 kDa, a single non-glycosylated polypeptide chain containing 87 amino acids. |
| Quantity | 5μg/20μg/1000μg |
| AA Sequence | VLEVYYTSLR CRCVQESSVF IPRRFIDRIQ ILPRGNGCPR KEIIVWKKNK SIVCVDPQAE WIQRMMEVLR KRSSSTLPVP VFKRKIP |
| Purity | > 97 % by SDS-PAGE and HPLC analyses. |
| Biological Activity | Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human B cells is in a concentration range of 1.0-10 ng/ml. |
| Physical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation | Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM PB, pH 7.4, 100 mM NaCl. |
| Endotoxin | Less than 1 EU/μg of rHuBCA-1/CXCL13 as determined by LAL method. |
| Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions. |
| Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. - 12 months from date of receipt, -20 to -70 °C as supplied. - 1 month, 2 to 8 °C under sterile conditions after reconstitution. - 3 months, -20 to -70 °C under sterile conditions after reconstitution. |
| Usage | This material is offered by Shanghai PrimeGene Bio-Tech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. |
| Reference | 1. Legler DF, Loetscher M, Roos RS, et al. 1998. J Exp Med. 187:655-60. 2. Gunn MD, Ngo VN, Ansel KM, et al. 1998. Nature. 391:799-803. 3. Ansel KM, Harris RB, Cyster JG. 2002. Immunity. 16:67-76. 4. Ansel KM, Ngo VN, Hyman PL, et al. 2000. Nature. 406:309-14. |
| Background | C-X-C motif chemokine 13 encoded by the CXCL13 gene located on human chromosome 4 is constitutively expressed in secondary lymphoid organs. It is also known as B lymphocyte chemoattractant (BLC). As its name suggests, CXCL13 is selectively chemotactic for B cells belonging to both the B-1 and B-2 subsets, and elicits its effects by interacting with chemokine receptor CXCR5. It and its receptor CXCR5 control the organization of B cells within follicles of lymphoid tissues. Recombinant human CXCL13 is a single non-glycosylated polypeptide chain containing 87 amino acids and mature human BCA-1 shares 64 % amino acid sequence similarity with the murine protein and 23–34 % amino acid sequence identity with other known CXC chemokines. |
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