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| 产地 | 中国 |
| 品牌 | PrimeGene（普欣） |
| 货号 | 661-01 |
| 用途 | 细胞/科研/抗肿瘤药物 |
| 包装规格 | 2μg |
| 纯度 | > 96 %% |
| CAS编号 | |
| 是否进口 | 否 |
产品名称：Recombinant Hirudin（rHirudin）
产品价格：
| 货号 | 规格 | 价格 |
| 661-01 | 2μg | 600 |
| 661-01 | 10μg | 1490 |
| 661-01 | 100μg | 4600 |
| 661-01 | 250μg | 8090 |
| 661-01 | 500μg | 13440 |
| 661-01 | 1mg | 19200 |
产品介绍：
| Accession | P84590 |
| Source | Pichia Pastoris |
| Molecular Weight | Approximately 6.7 kDa, a single non-glycosylated polypeptide chain containing 63 amino acid residues. |
| Quantity | 2μg/10μg/1000μg |
| AA Sequence | VVYTDCTESG QNLCLCEGSN VCGQGNKCIL GSDGEKNQCV TGEGTPGPQS HNDGDFEEPE EYL |
| Purity | > 96 % by SDS-PAGE and HPLC analyses. |
| Biological Activity | The biological activity is determined by chromogenic assay, 1 unit is defined as the amount of Hirudin that neutralizes 1 unit of the WHO preparation 89/588 of thrombin. The specific activity is no less than 14,000 ATU/mg protein. |
| Physical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20 mM PBS, pH 7.0, containing 2 % mannitol. |
| Endotoxin | Less than 1 EU/μg of rHirudin as determined by LAL method. |
| Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions. |
| Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. - 12 months from date of receipt, -20 to -70 °C as supplied. - 1 month, 2 to 8 °C under sterile conditions after reconstitution. - 3 months, -20 to -70 °C under sterile conditions after reconstitution. |
| Usage | This material is offered by Shanghai PrimeGene Bio-Tech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. |
| Reference | 1. Knapp A, Degenhardt T, Dodt J. 1992. J Biol Chem, 267: 24230-4. 2. Pineo GFandHull RD. 1995. Curr Opin Hematol, 2: 380-5. 3. Badimon L, Merino A, Badimon J, et al. 1991. Trends Cardiovasc Med, 1: 261-7. 4. Nasir MA, Toth CA, Mittra RA. 1996. Am J Ophthalmol, 121: 554-60. 5. Agnelli GandSonaglia F. 1997. Semin Thromb Hemost, 23: 143-8. |
| Background | Hirudin is the most potent natural thrombin-specific protease inhibitor, and is originally derived in the salivary glands of the medicinal leech. Unlike heparin, hirudin act directly on thrombin, rather than through other clotting factors. They have a high binding affinity and specificity for thrombin. Therefore, hirudin prevents or dissolves the formation of clots and thrombi, and has therapeutic value in blood coagulation disorders, in the treatment of skin hematomas and of superficial varicose veins, either as an injectable or a topical application cream. |
★高纯度、高蛋白活性
★低内毒素
★不同批次 产品稳定
★国内现货、高效快速
★Bio-Techne旗下品牌，品质保障
★无缝替代进口蛋白，质优价廉。
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