产品名称：Recombinant Human Interferon-gamma（rHuIFN-γ）

产品价格：

产品介绍：

Accession	P01579
GeneID	3458
Source	Escherichia coli.
Molecular Weight	Approximately 16.9 kDa, a single non-glycosylated polypeptide chain containing 144 amino acids.
Quantity	20μg/100μg/1000μg
AA Sequence	MQDPYVKEAE NLKKYFNAGH SDVADNGTLF LGILKNWKEE SDRKIMQSQI VSFYFKLFKN FKDDQSIQKS VETIKEDMNV KFFNSNKKKR DDFEKLTNYS VTDLNVQRKA IHELIQVMAE LSPAAKTGKR KRSQMLFRGR RASQ
Purity	> 98 % by SDS-PAGE and HPLC analyses.
Biological Activity	Fully biologically active when compared to standard. The ED50 as measured in anti-viral assays using human HeLa cells infected with encephalomyocarditis (EMC) virus is 0.15-0.80 ng/ml.
Physical Appearance	Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation	Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
Endotoxin	Less than 1 EU/μg of rHuIFN-γ as determined by LAL method.
Reconstitution	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Stability & Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. - 12 months from date of receipt, -20 to -70 °C as supplied. - 1 month, 2 to 8 °C under sterile conditions after reconstitution. - 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Usage	This material is offered by Shanghai PrimeGene Bio-Tech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.
SDS-PAGE
Reference	1. Pennino D, Bhavsar PK, Effner R, et al. 2012. J Allergy Clin Immunol, 2. Hibi M, Hachimura S, Ise W, et al. 2003. Cytotechnology, 43: 49-55. 3. Wang H, Ruan Z, Wang Y, et al. 2008. Mol Immunol, 45: 1548-56. 4. Kopinski P, Przybylski G, Jarzemska A, et al. 2007. Pol Merkur Lekarski, 23: 15-21.
Background	Interferon-gamma (IFN-γ), also known as Type II interferon or immune interferon, is a cytokine produced primarily by T-lymphocytes and natural killer cells. The protein shares no significant homology with IFN-β or the various IFN-α family proteins. Mature IFN-γ exists as noncovalently-linked homodimers. Human IFN-γ is highly species specific and is biologically active only in human and primate cells. IFN-γ was originally characterized based on its antiviral activities. The protein also exerts antiproliferative, immunoregulatory and proinflammatory activities and is thus important in host defense mechanisms. IFN-γ induces the production of cytokines, upregulates the expression of class I and II MHC antigens, Fc receptor and leukocyte adhesion molecules. It modulates macrophage effector functions, influences isotype switching and potentiates the secretion of immunoglobulins by B cells. IFN-γ also augments TH1 cell expansion and may be required for TH1 cell differentiation.

Primegene重组蛋白六大优势：

★高纯度、高蛋白活性

★低内毒素

★不同批次 产品稳定

★国内现货、高效快速

★Bio-Techne旗下品牌，品质保障

★无缝替代进口蛋白，质优价廉。

Primegene蛋白分装小贴士：

Primegene（普欣）是美国Bio-Techne（原R&D）旗下子品牌，专注于重组蛋白研发、生产， 产品涵盖分子生物学、蛋白化学、细胞生物学、免疫学等生命科学的诸多领域，拥有蛋白表达，菌种发酵，蛋白纯化，蛋白冻干以及抗体制备等完整的技术平台，并拥有自己的GMP中试生产车间。重组蛋白产品500多个，覆盖20余个物种及多项专利技术。

上海怡淼化学科技有限公司，作为美国Bio-Techne（原R&D）旗下子品牌Primegene（普欣）授权代理商，为抗肿瘤药物、细胞治疗、细胞培养、美容产品等领域的客户提供优质的产品和服务，同时可以提供：Perfemiker（博飞美科）、Sigma（西格玛）、Gibco、Jackson、TCI（梯希爱）、Alfa（阿法埃莎）、Acros、Thermo Fisher（赛默飞）等多种品牌，为您的科研提供一站式解决方案，欢迎咨询。

更多产品信息，请联系客服咨询。