|
| 产地 | 中国 |
| 品牌 | PrimeGene（普欣） |
| 货号 | 126-06 |
| 用途 | 细胞/科研/抗肿瘤药物 |
| 包装规格 | 20μg |
| 纯度 | > 96 %% |
| CAS编号 | |
| 是否进口 | 否 |
产品名称：Recombinant Murine Interferon-gamma（rMuIFN-γ）
产品价格：
| 货号 | 规格 | 价格 |
| 126-06 | 20μg | 600 |
| 126-06 | 100μg | 1490 |
| 126-06 | 250μg | 2830 |
| 126-06 | 500μg | 4370 |
| 126-06 | 1mg | 6470 |
产品介绍：
| Accession | P01580 |
| GeneID | 15978 |
| Source | Escherichia coli. |
| Molecular Weight | Approximately 15.5 kDa, a single non-glycosylated polypeptide chain containing 133 amino acids. |
| Quantity | 20μg/100μg/1000μg |
| AA Sequence | HGTVIESLES LNNYFNSSGI DVEEKSLFLD IWRNWQKDGD MKILQSQIIS FYLRLFEVLK DNQAISNNIS VIESHLITTF FSNSKAKKDA FMSIAKFEVN NPQVQRQAFN ELIRVVHQLL PESSLRKRKR SRC |
| Purity | > 96 % by SDS-PAGE and HPLC analyses. |
| Biological Activity | Fully biologically active when compared to standard. The ED50 as determined by an anti-viral assay using murine L929 cells infected with encephalomyocarditis (EMC) virus is less than 0.8 ng/ml, corresponding to a specific activity of > 1.3 × 106 IU/mg. |
| Physical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4, containing 5 % trehalose. |
| Endotoxin | Less than 1 EU/μg of rMuIFN-γ as determined by LAL method. |
| Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions. |
| Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. - 12 months from date of receipt, -20 to -70 °C as supplied. - 1 month, 2 to 8 °C under sterile conditions after reconstitution. - 3 months, -20 to -70 °C under sterile conditions after reconstitution. |
| Usage | This material is offered by Shanghai PrimeGene Bio-Tech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. |
| Reference | 1. Pennino D, Bhavsar PK, Effner R, et al. 2012. J Allergy Clin Immunol, 2. Hibi M, Hachimura S, Ise W, et al. 2003. Cytotechnology, 43: 49-55. 3. Wang H, Ruan Z, Wang Y, et al. 2008. Mol Immunol, 45: 1548-56. 4. Kopinski P, Przybylski G, Jarzemska A, et al. 2007. Pol Merkur Lekarski, 23: 15-21. |
| Background | Interferon-gamma (IFN-γ), also known as Type II interferon or immune interferon, is a cytokine produced primarily by T-lymphocytes and natural killer cells. The protein shares no significant homology with IFN-β or the various IFN-α family proteins. Mature IFN-γ exists as noncovalently-linked homodimers. It shares high sequence indentity with rat IFN-γ (86 %). IFN-γ was originally characterized based on its antiviral activities. The protein also exerts antiproliferative, immunoregulatory and proinflammatory activities and is thus important in host defense mechanisms. IFN-γ induces the production of cytokines, upregulates the expression of class I and II MHC antigens, Fc receptor and leukocyte adhesion molecules. It modulates macrophage effector functions, influences isotype switching and potentiates the secretion of immunoglobulins by B cells. Additionally, IFN-γ augments TH1 cell expansion and may be required for TH1 cell differentiation. |
★高纯度、高蛋白活性
★低内毒素
★不同批次 产品稳定
★国内现货、高效快速
★Bio-Techne旗下品牌，品质保障
★无缝替代进口蛋白，质优价廉。
更多产品信息，请联系客服咨询。
