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重组小鼠 rMuVEGF120 Primegene授权
  • 品牌:PrimeGene(普欣)
  • 产地:中国
  • 货号:125-06
  • 价格: ¥600/支
  • 发布日期: 2019-10-15
  • 更新日期: 2025-04-19
产品详请
产地 中国
品牌 PrimeGene(普欣)
货号 125-06
用途 细胞/科研/抗肿瘤药物
包装规格 2μg
纯度 > 96 %%
CAS编号
是否进口

产品名称:Recombinant Murine Vascular Endothelial Growth Factor 120(rMuVEGF120)

产品价格

货号规格价格
125-062μg600
125-0610μg1490
125-06100μg8600
125-06250μg15470
125-06500μg20120
125-061mg27520

产品介绍

SynonymsVascular endothelial growth factor isoform 120
AccessionQ00731
UnigeneMm.282184.
SourceEscherichia coli.
Molecular WeightApproximately 28.4 kDa, a disulfide-linked homodimeric protein consisting of two 121 amino acid polypeptide chains with Met at N-terminus.
Quantity2μg/10μg/1000μg
AA SequenceMAPTTEGEQK SHEVIKFMDV YQRSYCRPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCAGC CNDEALECVP TSESNITMQI MRIKPHQSQH IGEMSFLQHS RCECRPKKDR TKPEKCDKPR R
Purity> 96 % by SDS-PAGE and HPLC analyses.
Biological ActivityFully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human umbilical vein endothelial cells(HUVEC) is less than 5 ng/ml, corresponding to a specific activity of > 2.0 × 105 IU/mg.
Physical AppearanceSterile Filtered White lyophilized (freeze-dried) powder.
FormulationLyophilized from a 0.2 μm filtered solution in PBS, pH 7.4.
EndotoxinLess than 1 EU/μg of rMuVEGF120 as determined by LAL method.
ReconstitutionWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Stability & StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
UsageThis material is offered by Shanghai PrimeGene Bio-Tech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.
Reference1. Leung DW, Cachianes G, Kuang WJ, et al. 1989. Science. 246:1306-9.
2. Byrne AM, Bouchier-Hayes DJ, Harmey JH. 2005. J Cell Mol Med. 9:777-94.
3. Robinson CJ, Stringer SE. 2001. J Cell Sci. 114:853-65.
BackgroundVascular Endothelial Growth Factor is a sub-family of growth factors produced by cells that stimulates vasculogenesis and angiogenesis. VEGF's normal function is to create new blood vessels during embryonic development, new blood vessels after injury, muscle following exercise, and new vessels (collateral circulation) to bypass blocked vessels. VEGF signals through the three receptors: fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Mouse express alternately spliced isoforms of 120, 164, 182 amino acids (a.a.) in length. The VEGF120 shares 98 % a.a. sequence identity with corresponding regions of rat, 89 % with canine, feline, equine and porcine, and 87 % with human, ovine and bovine VEGF, respectively.

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